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| Nomenclature |
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Symbol:
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Tg(DRD1-ctxA)7Burt
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Name:
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transgene insertion 7, Frank H Burton
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MGI ID: |
MGI:3778286 |
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Synonyms: |
D1CT-7, Ticcy |
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Transgene:
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Tg(DRD1-ctxA)7Burt
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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BALB/c x C57BL/6
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The transgenic construct contains the cholera toxin intracellular enzymatic subunit A1 gene (ctxA) under the control of the 6.5 kb promoter of the human dopamine receptor D1, DRD1. Founder line 7 subsequently was established. Another female founder, 11, was produced but because this founder exhibited severe hyperreactivity in response to novel stimuli or introduction of potential mates, breeding this animal and estabilshing this line was precluded. (J:55492)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:55492
Campbell KM et al.,
"OCD-Like behaviors caused by a neuropotentiating transgene targeted to cortical and limbic D1+ neurons."
J Neurosci 1999 Jun 15;19(12):5044-53
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All: |
7 reference(s)
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Analysis Tools
