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| Nomenclature |
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Symbol:
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Pnpg
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Name:
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purine-nucleoside phosphorylase;
NP-1G
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MGI ID: |
MGI:3777975 |
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Synonyms: |
Np-1g |
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Gene:
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Pnp
Location:
Chr14:50944302-50953412 bp, + strand
Genetic Position: Chr14,
26.31 cM, cytoband B-C1
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Mutation
origin |
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Strain of Origin:
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C57BL/6J
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Mutation
description |
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Allele
Type: | |
Chemically induced (ENU) |
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Mutation: | |
Single point mutation |
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Mutation details: This allele was identified in the progeny of a cross between ENU mutagenized C57BL/6J males and C3H/HeHa females. A T to C transition occurred at nucleotide 46 resulting in a W16R amino acid change in the resulting protein. (J:522, J:39328)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Pnp Mutation:
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9 strains or lines available |
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| References |
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Original: |
J:522
Snyder FF,
"Genetic models of purine nucleoside phosphorylase deficiency in the mouse."
Adv Exp Med Biol 1991;309B():137-40
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All: |
3 reference(s)
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Analysis Tools
