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| Nomenclature |
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Symbol:
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Gt(ROSA)26Sortm1(ptxA)Cgh
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Name:
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gene trap ROSA 26, Philippe Soriano;
targeted mutation 1, Shaun R Coughlin
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MGI ID: |
MGI:3776029 |
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Synonyms: |
ROSA26PTX |
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Gene:
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Gt(ROSA)26Sor
Location:
Chr6:113067428-113077333 bp, - strand
Genetic Position: Chr6,
52.73 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:130781
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Parent Cell Line:
| E14 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (knock-in) |
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Mutation: | |
Insertion |
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Mutation details: A splice acceptor, floxed neo cassette and ptxA (pertussis toxin subunit 1) were knocked into intron 1. Removal of the neo cassette by cre-mediated recombination will result in the expresson of ptxA. (J:130781)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:130781
Regard JB et al.,
"Probing cell type-specific functions of Gi in vivo identifies GPCR regulators of insulin secretion."
J Clin Invest 2007 Dec;117(12):4034-43
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All: |
4 reference(s)
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Analysis Tools
