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| Nomenclature |
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Symbol:
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Esr2tm1.1Pcn
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Name:
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estrogen receptor 2 (beta);
targeted mutation 1.1, Pierre Chambon
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MGI ID: |
MGI:3775924 |
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Synonyms: |
ERbetaL2, ERbetaSTL2 |
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Gene:
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Esr2
Location:
Chr12:76120419-76177259 bp, - strand
Genetic Position: Chr12,
33.52 cM, cytoband D1-D3
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:132171
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Parent Cell Line:
| H1 (ES Cell) |
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Strain of Origin:
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129S2/SvPas
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Mutation description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: Germ-line, cre-mediated recombination was used to remove the neo cassette located downstream of exon 3 leaving exon 3 floxed. (J:132171)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Esr2 Mutation:
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8 strains or lines available |
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| References |
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Original: |
J:132171
Antal MC et al.,
"Sterility and absence of histopathological defects in nonreproductive organs of a mouse ERbeta-null mutant."
Proc Natl Acad Sci U S A 2008 Feb 19;105(7):2433-8
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All: |
3 reference(s)
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