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| Nomenclature |
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Symbol:
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Ip6k1tm1.1Snyd
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Name:
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inositol hexaphosphate kinase 1;
targeted mutation 1.1, Solomon Snyder
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MGI ID: |
MGI:3775918 |
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Synonyms: |
IP6K1- |
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Gene:
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Ip6k1
Location:
Chr9:108002501-108048780 bp, + strand
Genetic Position: Chr9,
59.07 cM, cytoband F2
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Impaired spermiogenesis in Ip6k1tm1.1Snyd/Ip6k1tm1.1Snyd mice
Show the 1 image(s) involving this allele.
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:132167
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129X1/SvJ
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Intragenic deletion |
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Mutation details: The first part of exon 6 that contains the C-terminal coding region was removed by germ-line, cre-mediated recombination. The absence of transcript was confirmed by RT-PCR analysis on brain and liver extracts. (J:132167)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Ip6k1 Mutation:
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40 strains or lines available |
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| References |
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Original: |
J:132167
Bhandari R et al.,
"Gene deletion of inositol hexakisphosphate kinase 1 reveals inositol pyrophosphate regulation of insulin secretion, growth, and spermiogenesis."
Proc Natl Acad Sci U S A 2008 Feb 19;105(7):2349-53
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All: |
4 reference(s)
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Analysis Tools
