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| Nomenclature |
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Symbol:
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Cops5tm1Rpar
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Name:
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COP9 (constitutive photomorphogenic) homolog, subunit 5 (Arabidopsis thaliana);
targeted mutation 1, Ruggero Pardi
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MGI ID: |
MGI:3775801 |
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Synonyms: |
CSN5fl, CSN5/JAB1flox |
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Gene:
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Cops5
Location:
Chr1:10024602-10038127 bp, - strand
Genetic Position: Chr1,
2.29 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:132114
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: An frt-flanked neo cassette with a 5' loxP site was inserted downstream of exon 2 and an additional loxP site was inserted upstream of exon 2. Germ-line, flp-mediated recombination was used to remove the neo cassette leaving a floxed exon 2. (J:132114)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Cops5 Mutation:
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7 strains or lines available |
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| References |
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Original: |
J:132114
Panattoni M et al.,
"Targeted inactivation of the COP9 signalosome impairs multiple stages of T cell development."
J Exp Med 2008 Feb 18;205(2):465-77
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All: |
4 reference(s)
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Analysis Tools
