|
|
| Nomenclature |
|
Symbol:
|
Flcntm1.1Lss
|
|
Name:
|
folliculin;
targeted mutation 1.1, Laura S Schmidt
|
|
MGI ID: |
MGI:3774416 |
|
Synonyms: |
BHDd |
|
Gene:
|
Flcn
Location:
Chr11:59791408-59810016 bp, - strand
Genetic Position: Chr11,
37.79 cM
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:130978
|
|
Parent Cell Line:
| Not Specified (ES Cell) |
|
Strain of Origin:
|
Not Specified
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutation: | |
Intragenic deletion |
| |
|
Mutation details: Exon 7 was removed by germ-line, cre-mediated recombination. Deletion of exon 7 results in a frame shift and premature termination. This allele is expected to be null. (J:130978)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
Carrying any Flcn Mutation:
|
10 strains or lines available |
|
| References |
|
Original: |
J:130978
Baba M et al.,
"Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys."
J Natl Cancer Inst 2008 Jan 16;100(2):140-54
|
|
All: |
3 reference(s)
|
|
Analysis Tools
