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| Nomenclature |
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Symbol:
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Flcntm1Baba
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Name:
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folliculin;
targeted mutation 1, Masaya Baba
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MGI ID: |
MGI:3774414 |
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Synonyms: |
BHDf, Flcntm1Lss |
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Gene:
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Flcn
Location:
Chr11:59791408-59810016 bp, - strand
Genetic Position: Chr11,
37.79 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:130978
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A frt-flanked and floxed neo cassette was inserted into inton 6 and an additional loxP site was inserted into intron 7. The neo cassette was removed by germ-line, flp-mediated recombination to yield a floxed exon 7. (J:130978)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Flcn Mutation:
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10 strains or lines available |
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| References |
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Original: |
J:130978
Baba M et al.,
"Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys."
J Natl Cancer Inst 2008 Jan 16;100(2):140-54
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All: |
4 reference(s)
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Analysis Tools
