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| Nomenclature |
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Symbol:
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Rtn4rtm1Gogo
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Name:
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reticulon 4 receptor;
targeted mutation 1, Joseph A Gogos
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MGI ID: |
MGI:3774128 |
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Gene:
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Rtn4r
Location:
Chr16:18127642-18152408 bp, + strand
Genetic Position: Chr16,
11.23 cM, cytoband B1
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:130368
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129
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Mutation description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exon 2 of the gene locus was replaced with a self excising selection cassette containing a neomycin resistance gene. After germline transmission, the cassette was removed leaving a loxP site in place of exon 2. Gene inactivation was confirmed by RT-PCR of brain RNA. (J:130368)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Rtn4r Mutation:
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6 strains or lines available |
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| References |
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Original: |
J:130368
Hsu R et al.,
"Nogo Receptor 1 (RTN4R) as a Candidate Gene for Schizophrenia: Analysis Using Human and Mouse Genetic Approaches."
PLoS ONE 2007;2(11):e1234
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All: |
2 reference(s)
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