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| Nomenclature |
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Symbol:
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Adora2btm1Dgen
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Name:
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adenosine A2b receptor;
targeted mutation 1, Deltagen
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MGI ID: |
MGI:3773754 |
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Synonyms: |
A2BAR-, A2BKO |
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Gene:
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Adora2b
Location:
Chr11:62248984-62266453 bp, + strand
Genetic Position: Chr11,
37.96 cM, cytoband B2
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:131444
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A fragment from 112 bp to 267 bp of the coding region was replaced with an IRES-lacZ and neo cassette. The absence of transcript expression was confirmed by real-time RT-PCR on cardiac tissue extracts. This allele is also a null allele. (J:131444)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Adora2b Mutation:
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3 strains or lines available |
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| References |
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Original: |
J:131444
Eckle T et al.,
"Cardioprotection by ecto-5'-nucleotidase (CD73) and A2B adenosine receptors."
Circulation 2007 Mar 27;115(12):1581-90
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All: |
20 reference(s)
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Analysis Tools
