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| Nomenclature |
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Symbol:
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Myocdtm1Msp
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Name:
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myocardin;
targeted mutation 1, Michael S Parmacek
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MGI ID: |
MGI:3773717 |
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Gene:
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Myocd
Location:
Chr11:65176561-65269941 bp, - strand
Genetic Position: Chr11,
40.42 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:131288
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129/Sv
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A neo cassette with a 3' loxP site was inserted into intron 8 and an additional loxP site was inserted into intron 7. (J:131288)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Myocd Mutation:
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4 strains or lines available |
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| References |
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Original: |
J:131288
Huang J et al.,
"Myocardin regulates expression of contractile genes in smooth muscle cells and is required for closure of the ductus arteriosus in mice."
J Clin Invest 2008 Feb;118(2):515-25
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All: |
3 reference(s)
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Analysis Tools
