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| Nomenclature |
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Symbol:
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Bnc1tm1.1Tsen
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Name:
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basonuclin 1;
targeted mutation 1.1, Hung Tseng
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MGI ID: |
MGI:3771811 |
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Synonyms: |
Bnc1- |
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Gene:
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Bnc1
Location:
Chr7:81966672-81992299 bp, - strand
Genetic Position: Chr7,
45.71 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:130266
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Intragenic deletion |
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Mutation details: Exon 4 was removed by germ-line, cre-mediated recombination resulting a premature stop codon and a frame shift. The absence of transcript was confirmed by RT-PCR and the absence of protein product was confirmed by immunohistochemistry. (J:130266)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Bnc1 Mutation:
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2 strains or lines available |
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| References |
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Original: |
J:130266
Zhang X et al.,
"Basonuclin-null mutation impairs homeostasis and wound repair in mouse corneal epithelium."
PLoS ONE 2007;2(10):e1087
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All: |
2 reference(s)
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