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| Nomenclature |
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Symbol:
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Tg(Igh-Lmp2a)13FRdni
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Name:
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transgene insertion 13F, R D Nicholls
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MGI ID: |
MGI:3769767 |
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Synonyms: |
EmuLMP2A, TgPWS/AS(del) |
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Transgene:
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Tg(Igh-Lmp2a)13FRdni
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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C57BL/6 x SJL
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The Ig heavy chain promoter with Emu enhancer element was used to drive the expression of the Epstein-Barr virus latent membrane protein 2A. Expression was confirmed by RT-PCR of brain extracts. (J:56614)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Notes |
9 lines were created with the eight others exhibiting lymphocyte cell lineage defects. Line 13F results in a deletion in chromosome 7 from Mkrn3 to Herc2 (Mkrn3, Ndn, Snurf/Snrpn, Ube3a, and Herc2 are deleted).
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| References |
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Original: |
J:56614
Gabriel JM et al.,
"A transgene insertion creating a heritable chromosome deletion mouse model of Prader-Willi and angelman syndromes."
Proc Natl Acad Sci U S A 1999 Aug 3;96(16):9258-63
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All: |
5 reference(s)
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Analysis Tools
