|
|
| Nomenclature |
|
Symbol:
|
Tg(Lck-Jak3)2Ljb
|
|
Name:
|
transgene insertion 2, Leslie J Berg
|
|
MGI ID: |
MGI:3769343 |
|
Synonyms: |
Tgthy |
|
Transgene:
|
Tg(Lck-Jak3)2Ljb
Location:
unknown
|
|
Transgene
origin |
|
Strain of Origin:
|
(C57BL/6 x C3H)F2
|
|
Transgene
description |
|
Transgene
Type: | |
Transgenic (random, expressed) |
|
Mutation: | |
Insertion |
| |
|
Mutation details: This transgene expresses a murine Jak3 cDNA under the control of the Lck proximal promoter. Transgene expression is initially detected in the thymocytes and peripheral T cells but is gradually lost in peripheral T cells. (J:128694)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
| References |
|
Original: |
J:128694
Thomis DC et al.,
"Peripheral expression of Jak3 is required to maintain T lymphocyte function."
J Exp Med 1997 Jan 20;185(2):197-206
|
|
All: |
2 reference(s)
|
|
Analysis Tools
