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| Nomenclature |
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Symbol:
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Tg(CAG-AR*97Q)7-8Sobu
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Name:
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transgene insertion 7-8, Gen Sobue
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MGI ID: |
MGI:3767716 |
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Synonyms: |
AR-97Q, Tg(ACTB-AR*97Q)7-8Sobu |
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Transgene:
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Tg(CAG-AR*97Q)7-8Sobu
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(C57BL/6 x DBA/2)F1
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The chicken actin promoter with a CMV enhancer (CAGGS) was used to drive the expression of a human androgen receptor open reading frame that contained a block of 97 CAG repeats. (J:128619)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Notes |
Five lines were created (2-6, 4-6, 7-8, 3-7, 8-5) with copy numbers of the transgene ranging from 1 to 3 in lines 2-6, 4-6 and 7-8. Lines are phenotypically identical and line 7-8 was selected as the representative line as it was used in a subsequent publication by the same author.
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| References |
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Original: |
J:128619
Katsuno M et al.,
"Testosterone reduction prevents phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy."
Neuron 2002 Aug 29;35(5):843-54
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All: |
5 reference(s)
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Analysis Tools
