|
|
| Nomenclature |
|
Symbol:
|
Paxip1tm2Gdr
|
|
Name:
|
PAX interacting (with transcription-activation domain) protein 1;
targeted mutation 1, Gregory R Dressler
|
|
MGI ID: |
MGI:3767658 |
|
Synonyms: |
ptipfl, PTIPflox, ptiploxP |
|
Gene:
|
Paxip1
Location:
Chr5:27740667-27791339 bp, - strand
Genetic Position: Chr5,
13.23 cM, cytoband A3
|
|
Mutation origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:128440
|
|
Parent Cell Line:
| R1 (ES Cell) |
|
Strain of Origin:
|
(129X1/SvJ x 129S1/Sv)F1-Kitl+
|
|
Mutation description |
|
Allele
Type: | |
Targeted (Floxed/Frt) |
|
Mutation: | |
Insertion |
| |
|
Mutation details: A neo cassette flanked by FRT sites was inserted upstream of exon 1 and an additional loxP site was inserted downstream of exon 1. The neo cassette was subsequently removed by flp-mediated recombination. (J:128440, J:148599)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
| References |
|
Original: |
J:128440
Patel SR et al.,
"The BRCT-domain containing protein PTIP links PAX2 to a histone H3, lysine 4 methyltransferase complex."
Dev Cell 2007 Oct;13(4):580-92
|
|
All: |
9 reference(s)
|
|