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| Nomenclature |
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Symbol:
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Gabrb3tm2.1Geh
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Name:
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gamma-aminobutyric acid (GABA) A receptor, subunit beta 3;
targeted mutation 2.1, Gregg E Homanics
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MGI ID: |
MGI:3767248 |
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Synonyms: |
beta3F |
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Gene:
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Gabrb3
Location:
Chr7:57590518-57828802 bp, + strand
Genetic Position: Chr7,
33.53 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:127877
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: Gabrb3tm2Geh heterozygous mice with a floxed exon 3 and neomycin cassette allele (Fneo) were bred to Tg(ACTFLPe)9205Dym actin-FLPe mice to remove the Neomycin cassette. (J:127877)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:127877
Ferguson C et al.,
"New insight into the role of the beta3 subunit of the GABAA-R in development, behavior, body weight regulation, and anesthesia revealed by conditional gene knockout."
BMC Neurosci 2007;8():85
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All: |
3 reference(s)
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Analysis Tools
