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| Nomenclature |
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Symbol:
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Tg(Ins2-H2-Ead,Ins2-H2-Eb1b)187-7Bri
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Name:
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transgene insertion 187-7, Ralph L Brinster
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MGI ID: |
MGI:3766019 |
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Synonyms: |
I-E, Ins-IE, Insl-E |
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Transgene:
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Tg(Ins2-H2-Ead,Ins2-H2-Eb1b)187-7Bri
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(C57BL/6 x SJL)F1
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: 2 independent constructs consisting of a 600 bp fragment of the 5' sequences driving the H2-Ead and a 600 bp fragment of 5' sequence driving the H2-Eb1b gene were coinjected into fertilized pronuclei. Four founders with germline transmission were identified and 3 (187-1, 187-7, and 190-5) were further studied. 187-7 (male) was chosen as representative, since it apparently characterized most thoroughly. (J:127706)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:127706
Lo D et al.,
"Diabetes and tolerance in transgenic mice expressing class II MHC molecules in pancreatic beta cells."
Cell 1988 Apr 8;53(1):159-68
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All: |
3 reference(s)
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Analysis Tools
