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| Nomenclature |
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Symbol:
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Tg(Th-SNCA*)1.2Ccs
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Name:
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transgene insertion 1.2, Christine C Stichel
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MGI ID: |
MGI:3764815 |
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Synonyms: |
msTH, THsyn |
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Transgene:
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Tg(Th-SNCA*)1.2Ccs
Location:
unknown
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: This transgene contains a double mutant human SNCA with amino acid substitutions of proline for alanine at position 30 (A30P) and threonine for alanine at position 53 (A53T) under the control of a mouse tyrosine hydroxylase promoter. Expression is detected in the brain. (J:127708)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Notes |
Two lines were created with similar expression patterns and line 1.2 was choosen as the representative line.
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| References |
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Original: |
J:127708
Maskri L et al.,
"Influence of different promoters on the expression pattern of mutated human alpha-synuclein in transgenic mice."
Neurodegener Dis 2004;1(6):255-65
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All: |
3 reference(s)
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Analysis Tools
