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| Nomenclature |
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Symbol:
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Ptch1tm1Hahn
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Name:
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patched homolog 1;
targeted mutation 1, Heidi Hahn
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MGI ID: |
MGI:3764517 |
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Synonyms: |
Ptchflox |
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Gene:
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Ptch1
Location:
Chr13:63511533-63565520 bp, - strand
Genetic Position: Chr13,
32.8 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:127207
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A loxP site was inserted into intron 7 and a second loxP site followed by a frt-flanked neo cassette was inserted into intron 9. Insertion was confirmed by Southern blot analysis and PCR genotyping. (J:127207)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:127207
Uhmann A et al.,
"The Hedgehog receptor Patched controls lymphoid lineage commitment."
Blood 2007 Sep 15;110(6):1814-23
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All: |
7 reference(s)
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Analysis Tools
