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| Nomenclature |
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Symbol:
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Tg(KRT14-Il1f6)1Hblu
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Name:
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transgene insertion 1, Hal Blumberg
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MGI ID: |
MGI:3762035 |
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Transgene:
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Tg(KRT14-Il1f6)1Hblu
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(C57BL/6 x DBA/2)F2
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The promoter of human KRT14 drives the expression of mouse Il1f5 in basal keratinocytes. At least 70-fold higher mRNA expression compared to in wild-type was detected in mice expressing this transgene. (J:126327)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Notes |
9 founders were used to create 4 lines with at least 70-fold higher mRNA expression.
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| References |
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Original: |
J:126327
Blumberg H et al.,
"Opposing activities of two novel members of the IL-1 ligand family regulate skin inflammation."
J Exp Med 2007 Oct 29;204(11):2603-14
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All: |
2 reference(s)
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Analysis Tools
