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| Nomenclature |
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Symbol:
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Cyldtm1Awai
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Name:
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cylindromatosis (turban tumor syndrome);
targeted mutation 1, Ari Waisman
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MGI ID: |
MGI:3761621 |
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Synonyms: |
CYLDF |
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Gene:
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Cyld
Location:
Chr8:88697028-88751945 bp, + strand
Genetic Position: Chr8,
43.51 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:126113
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A floxed neo was insert upstream of exoon 7 and an additional loxP site downstream of exon 7. The neo cassette was subsequently removed by cre-mediated recombination using a transient transfection of a cre-expressing plasmid. Insertion was confirmed by Southern blot. (J:126113)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Cyld Mutation:
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3 strains or lines available |
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| References |
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Original: |
J:126113
Hovelmeyer N et al.,
"Regulation of B cell homeostasis and activation by the tumor suppressor gene CYLD."
J Exp Med 2007 Oct 29;204(11):2615-27
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All: |
1 reference(s)
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Analysis Tools
