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| Nomenclature |
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Symbol:
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Ppp2r3ctm1Imku
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Name:
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protein phosphatase 2, regulatory subunit B'', gamma;
targeted mutation 1, Nobuo Sakaguchi
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MGI ID: |
MGI:3759678 |
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Synonyms: |
G5prF |
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Gene:
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Ppp2r3c
Location:
Chr12:55280814-55303000 bp, - strand
Genetic Position: Chr12,
23.9 cM, cytoband C1
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:100706
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A loxP site was inserted upstream of exon 1 and a floxed neo cassette downstream of exon 2. Insertion was confirmed by Southern blot analysis. Cre-mediated recombination can remove the first 2 exons and result in an absence of transcript, as confirmed by RT-PCR. (J:100706)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Ppp2r3c Mutation:
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23 strains or lines available |
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| References |
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Original: |
J:100706
Xing Y et al.,
"Protein phosphatase subunit G5PR is needed for inhibition of B cell receptor-induced apoptosis."
J Exp Med 2005 Sep 5;202(5):707-19
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All: |
2 reference(s)
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Analysis Tools
