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| Nomenclature |
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Symbol:
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Tg(Camk2a-cre/ERT2)2Gsc
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Name:
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transgene insertion 2, Gunther Schutz
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MGI ID: |
MGI:3759305 |
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Synonyms: |
CaMKCreERT2, Tg(Camk2a-cre/ESR1)2Gsc |
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Transgene:
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Tg(Camk2a-cre/ERT2)2Gsc
Location:
unknown
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Transgene
origin |
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Transgene
description |
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Transgene
Type: | |
Transgenic (Cre/Flp) |
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Mutation: | |
Insertion |
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Mutation details: The Camk2a promoter was used to drive expression of a cre and human estrogen receptor fusion (cre/ESR1). Expression is inducible by tamoxifen and localizes to the neurons of the adult forebrain. (J:125230)
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Recombinase activity
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
Three lines were created (lines 1, 2 and 3) with 1, 2 and 4 copy numbers of the transgene, respectively. Line 2 was choosen as the representative line because while copy number affects the level of expression similar phenotypes are produced and the majority of the reporting in J:125230 focuses on line 2.
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| References |
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Original: |
J:125230
Erdmann G et al.,
"Inducible gene inactivation in neurons of the adult mouse forebrain."
BMC Neurosci 2007;8():63
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All: |
11 reference(s)
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Analysis Tools
