|
|
| Nomenclature |
|
Symbol:
|
Tg(GSK3B*S9A)1Vln
|
|
Name:
|
transgene insertion 1, Fred Fan Leuven
|
|
MGI ID: |
MGI:3722095 |
|
Synonyms: |
GSK-3B(S9A) |
|
Transgene:
|
Tg(GSK3B*S9A)1Vln
Location:
unknown
|
|
Transgene
origin |
|
Transgene
description |
|
Transgene
Type: | |
Transgenic (random, expressed) |
|
Mutation: | |
Insertion |
| |
|
Mutation details: DNA coding for human GSK-3B(S9A) was ligated into a vector based on the mouse Thy1 gene and was microinjected into 0.5-day old FVB/N prenuclear mouse embryos. Expression of human GSK3B protein was demonstrated by Western blot in the brain and spinal cord of the mice. (J:100971)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
| References |
|
Original: |
J:100971
Spittaels K et al.,
"Glycogen synthase kinase-3beta phosphorylates protein tau and rescues the axonopathy in the central nervous system of human four-repeat tau transgenic mice."
J Biol Chem 2000 Dec 29;275(52):41340-9
|
|
All: |
3 reference(s)
|
|
Analysis Tools
