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| Nomenclature |
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Symbol:
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Glis2tm1Tre
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Name:
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GLIS family zinc finger 2;
targeted mutation 1, Mathias Treier
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MGI ID: |
MGI:3719836 |
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Synonyms: |
Glis2lacZ |
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Gene:
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Glis2
Location:
Chr16:4594713-4624924 bp, + strand
Genetic Position: Chr16,
2.45 cM, cytoband A1-B1
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:123510
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Parent Cell Line:
| E14.1 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A targeting vector was designed to replace exons 3-5 with an in-frame lacZ with the self-excisable neo cassette (ACN). (J:123510)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Glis2 Mutation:
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81 strains or lines available |
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| References |
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Original: |
J:123510
Attanasio M et al.,
"Loss of GLIS2 causes nephronophthisis in humans and mice by increased apoptosis and fibrosis."
Nat Genet 2007 Aug;39(8):1018-24
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All: |
1 reference(s)
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Analysis Tools
