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| Nomenclature |
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Symbol:
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Ramp2tm1Kmca
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Name:
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receptor (calcitonin) activity modifying protein 2;
targeted mutation 1, Kathleen Caron
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MGI ID: |
MGI:3718497 |
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Synonyms: |
Ramp2- |
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Gene:
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Ramp2
Location:
Chr11:101246028-101259546 bp, + strand
Genetic Position: Chr11,
64.47 cM
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Developmental cardiovascular defects in Ramp2tm1Kmca/Ramp2tm1Kmca embryos
Show the 4 image(s) involving this allele.
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:123382
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Parent Cell Line:
| TC1/TC-1 (ES Cell) |
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Strain of Origin:
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129S6/SvEvTac
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: The promoter region and exons 1 and 2 were replaced with the neomycin resistance cassette. Quantitative RT-PCR did not detect transcripts in mutant embryonic RNA extracts. (J:123382)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Ramp2 Mutation:
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2 strains or lines available |
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| References |
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Original: |
J:123382
Dackor R et al.,
"Receptor activity-modifying proteins 2 and 3 have distinct physiological functions from embryogenesis to old age."
J Biol Chem 2007 Jun 22;282(25):18094-9
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All: |
2 reference(s)
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Analysis Tools
