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| Nomenclature |
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Symbol:
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Tg(Ckm-DGAT2)10Far
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Name:
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transgene insertion 10, Bob Farese
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MGI ID: |
MGI:3717406 |
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Synonyms: |
MCK-DGAT2 |
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Transgene:
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Tg(Ckm-DGAT2)10Far
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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C57BL/6NHsd
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The targeting construct was designed with 4 kb of the mouse muscle creatine kinase (MCK) promoter sequence placed upstream of a 1.2 kb human acyl-CoA:diacylglycerol acyltransferase 2 (DGAT2) cDNA sequence, followed by a 2.2 kb human growth hormone minigene (providing the polyA signal). The transgene was microinjected into C57BL/6NHsd fertilized eggs and the resulting transgenic offspring were bred to C57BL/6NHsd. Founder line 10 mice were established. (J:129495)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:129495
Levin MC et al.,
"Increased lipid accumulation and insulin resistance in transgenic mice expressing DGAT2 in glycolytic (type II) muscle."
Am J Physiol Endocrinol Metab 2007 Dec;293(6):E1772-81
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All: |
1 reference(s)
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Analysis Tools
