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| Nomenclature |
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Symbol:
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Shc1tm9.1Paw
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Name:
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src homology 2 domain-containing transforming protein C1;
targeted mutation 9.1, Tony Pawson
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MGI ID: |
MGI:3717010 |
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Synonyms: |
Shc1KO |
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Gene:
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Shc1
Location:
Chr3:89418443-89430015 bp, + strand
Genetic Position: Chr3,
39.11 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:122927
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Intragenic deletion |
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Mutation details: The floxed region was excised via Cre-mediated recombination. No protein is produced from this allele. (J:122927)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Shc1 Mutation:
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45 strains or lines available |
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| References |
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Original: |
J:122927
Hardy WR et al.,
"Combinatorial ShcA docking interactions support diversity in tissue morphogenesis."
Science 2007 Jul 13;317(5835):251-6
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All: |
1 reference(s)
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