|
|
| Nomenclature |
|
Symbol:
|
Shc1tm5Paw
|
|
Name:
|
src homology 2 domain-containing transforming protein C1;
targeted mutation 5, Tony Pawson
|
|
MGI ID: |
MGI:3716779 |
|
Synonyms: |
ShcA2F |
|
Gene:
|
Shc1
Location:
Chr3:89418443-89430015 bp, + strand
Genetic Position: Chr3,
39.11 cM
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:122927
|
|
Parent Cell Line:
| R1 (ES Cell) |
|
Strain of Origin:
|
(129X1/SvJ x 129S1/Sv)F1-Kitl+
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (knock-in) |
|
Mutation: | |
Insertion |
| |
|
Mutation details: A targeting vector was used to insert cDNA containing Y239/240F substitutions with a single Flag-pA epitope tag and a floxed neo into exon 3, replacing the exon 4 of the locus. (J:122927)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
Carrying any Shc1 Mutation:
|
45 strains or lines available |
|
| References |
|
Original: |
J:122927
Hardy WR et al.,
"Combinatorial ShcA docking interactions support diversity in tissue morphogenesis."
Science 2007 Jul 13;317(5835):251-6
|
|
All: |
3 reference(s)
|
|
Analysis Tools
