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| Nomenclature |
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Symbol:
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Tg(AMELX-LRAP)9Gibs
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Name:
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transgene insertion 9, Carolyn Gibson
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MGI ID: |
MGI:3716151 |
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Transgene:
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Tg(AMELX-LRAP)9Gibs
Location:
unknown
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Transgene origin |
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Strain of Origin:
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C57BL/6 x SJL
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Transgene description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: 5.5 kb of upstream bovine AMELX gene sequence plus untranslated exon 1 and intron 1 was fused to a bovine LRAP cDNA, and followed by a bovine polyadenylation signal sequence from the bovine AMELX gene. RT-PCR analysis demonstrated that this transgene is expressed in tooth germ by 15 days of fetal age, and western blot analysis demonstrated protein expression in molar tooth germs. Four lines of transgenice mice were produced; in addition to line 9, lines 15, 16 and 22 were made. (J:122916)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:122916
Chen E et al.,
"The small bovine amelogenin LRAP fails to rescue the amelogenin null phenotype."
Calcif Tissue Int 2003 Nov;73(5):487-95
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All: |
1 reference(s)
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