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| Nomenclature |
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Symbol:
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Dp(16Lipi-Zfp295)1Yey
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Name:
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duplication, Chr 16, Y Eugene Yu 1
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MGI ID: |
MGI:3714529 |
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Synonyms: |
Dp(16)1Yey, Dp(16)1Yu, Dp(16D930038D03Tik-Zfp295)1Yey, Dp(16Lipi-Zfp295)1Yey, Dp1Yu, Ts1Yey |
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Gene:
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Dp(16Lipi-Zfp295)1Yey
Location:
unknown
Genetic Position: Chr16,
Syntenic
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:121790
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Parent Cell Line:
| AB2.2 (ES Cell) |
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Strain of Origin:
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129S7/SvEvBrd-Hprtb-m2
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Mutation
description |
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Allele
Type: | |
Targeted (knock-in) |
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Mutation: | |
Duplication |
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Mutation details: A 22.9Mb region of chromosome 16 that is syntenic with human chromosome 21 was duplicated using a Cre/loxP-mediated recombination system. This region, thought to be involved in Down's Syndrome, contains 113 orthologues including all markers between and including D930038D03Rik and Zfp295. (J:121790)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:121790
Li Z et al.,
"Duplication of the entire 22.9 Mb human chromosome 21 syntenic region on mouse chromosome 16 causes cardiovascular and gastrointestinal abnormalities."
Hum Mol Genet 2007 Jun 1;16(11):1359-66
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All: |
6 reference(s)
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Analysis Tools
