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| Nomenclature |
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Symbol:
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Cby1tm1Ktkm
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Name:
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chibby homolog 1 (Drosophila);
targeted mutation 1, Ken-Ichi Takemaru
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MGI ID: |
MGI:3714454 |
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Synonyms: |
Cby- |
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Gene:
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Cby1
Location:
Chr15:79659227-79667660 bp, + strand
Genetic Position: Chr15,
37.84 cM, cytoband E2
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Small size and postnatal lethality of Cby1tm1Ktkm/Cby1tm1Ktkm mice
Show the 3 image(s) involving this allele.
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:122334
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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The coding region was replaced with a neo cassette. (J:147413)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
Phenotypic Similarity to Human Syndrome: Primary Ciliary Dyskinesia (J:147413, J:166685).
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| References |
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Original: |
J:122334
Li FQ et al.,
"Chibby promotes adipocyte differentiation through inhibition of beta-catenin signaling."
Mol Cell Biol 2007 Jun;27(12):4347-54
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All: |
3 reference(s)
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Analysis Tools
