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| Nomenclature |
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Symbol:
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Tg(Myh6-rtTA)8585Jam
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Name:
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transgene insertion 8585, John A McDonald
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MGI ID: |
MGI:3712947 |
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Synonyms: |
JAM8585, Tg(Myh6-rtTA)1Jam |
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Transgene:
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Tg(Myh6-rtTA)8585Jam
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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FVB/NTac
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: A codon optimized version (for mammalian translation) of the reverse tetracycline transactivator was cloned behind the 5.5kb alpha myosin heavy chain promoter. Reporter construct assays showed that this transgene is uniformly transcribed in cardiac myocytes, and not in various other tissues tested. (J:70619)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:70619
Valencik ML et al.,
"Codon optimization markedly improves doxycycline regulated gene expression in the mouse heart."
Transgenic Res 2001 Jun;10(3):269-75
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All: |
6 reference(s)
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Analysis Tools
