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| Nomenclature |
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Symbol:
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Tg(Aqp2-cre)1Dek
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Name:
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transgene insertion 1, Donald E Kohan
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MGI ID: |
MGI:3712435 |
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Synonyms: |
AQP2-Cre |
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Transgene:
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Tg(Aqp2-cre)1Dek
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(C57BL/6 x SJL)F2
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Transgene
description |
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Transgene
Type: | |
Transgenic (Cre/Flp) |
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Mutation: | |
Insertion |
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Mutation details: This transgene contains a 9.5 kb fragment of the mouse aquaporin 2 gene 5'-flanking region placed upstream of a Cre recombinase sequence (with SV40 nuclear localization signal at the amino terminus and an 11-amino acid epitope tag derived from Herpes simplex virus glycoprotein D located at the carboxy terminus). The aquaporin regulatory sequences drive Cre expression in the collecting ducts of the kidney and in sperm. (J:104785)
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Recombinase activity
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:104785
Ge Y et al.,
"Collecting duct-specific knockout of endothelin-1 alters vasopressin regulation of urine osmolality."
Am J Physiol Renal Physiol 2005 May;288(5):F912-20
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All: |
4 reference(s)
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Analysis Tools
