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| Nomenclature |
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Symbol:
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Col17a1tm1Shzu
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Name:
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collagen, type XVII, alpha 1;
targeted mutation 1, Hiroshi Shimizu
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MGI ID: |
MGI:3711776 |
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Synonyms: |
Col17m- |
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Gene:
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Col17a1
Location:
Chr19:47646344-47692094 bp, - strand
Genetic Position: Chr19,
40.07 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:121695
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129/SvEv
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exon 2 was replaced with a PGK-neo cassette by homologous recombination. Northern blot confirmed absence of transcript in mutant karatinocytes, and Western blot confirmed absence of protein. (J:121695)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Col17a1 Mutation:
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0 strains or lines available |
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| References |
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Original: |
J:121695
Nishie W et al.,
"Humanization of autoantigen."
Nat Med 2007 Mar;13(3):378-83
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All: |
8 reference(s)
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Analysis Tools
