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| Nomenclature |
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Symbol:
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Cxadrtm1Mds
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Name:
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coxsackie virus and adenovirus receptor;
targeted mutation 1, Michael D Schneider
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MGI ID: |
MGI:3711225 |
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Synonyms: |
CarF |
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Gene:
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Cxadr
Location:
Chr16:78301496-78359785 bp, + strand
Genetic Position: Chr16,
45.28 cM, cytoband C
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:121400
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: Exon 2 was flanked by loxP sites. This exon encodes part of the secretion signal sequence as well as much of the extracellular immunoglobulin-like domain 1. Deletion of this exon results in a frame shift and premature termination. A frt-flanked neo was included in the vector. (J:121400)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Cxadr Mutation:
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2 strains or lines available |
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| References |
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Original: |
J:121400
Chen JW et al.,
"Cardiomyocyte-specific deletion of the coxsackievirus and adenovirus receptor results in hyperplasia of the embryonic left ventricle and abnormalities of sinuatrial valves."
Circ Res 2006 Apr 14;98(7):923-30
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All: |
1 reference(s)
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Analysis Tools
