|
|
| Nomenclature |
|
Symbol:
|
Cks1btm1Sir
|
|
Name:
|
CDC28 protein kinase 1b;
targeted mutation 1, Steven I Reed
|
|
MGI ID: |
MGI:3711167 |
|
Synonyms: |
Cks1- |
|
Gene:
|
Cks1b
Location:
Chr3:89415472-89418383 bp, - strand
Genetic Position: Chr3,
39.11 cM
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:121692
|
|
Parent Cell Line:
| Not Specified (ES Cell) |
|
Strain of Origin:
|
Not Specified
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutations: | |
Insertion, Intragenic deletion |
| |
|
Exon 2, which encodes 55% of the protein, was replaced with a neomycin resistance cassette. (J:121692)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
Carrying any Cks1b Mutation:
|
7 strains or lines available |
|
| References |
|
Original: |
J:121692
Spruck C et al.,
"A CDK-independent function of mammalian Cks1: targeting of SCF(Skp2) to the CDK inhibitor p27Kip1."
Mol Cell 2001 Mar;7(3):639-50
|
|
All: |
5 reference(s)
|
|
Analysis Tools
