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| Nomenclature |
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Symbol:
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Slc16a2tm1Dgen
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Name:
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solute carrier family 16 (monocarboxylic acid transporters), member 2;
targeted mutation 1, Deltagen
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MGI ID: |
MGI:3710233 |
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Synonyms: |
Mct8- |
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Gene:
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Slc16a2
Location:
ChrX:103697414-103821965 bp, - strand
Genetic Position: ChrX,
46.29 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:120737
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A 33 bp-fragment of exon 2 was replaced with a lacZ-neo cassette. Absence of protein was confirmed by Western blot of mutant liver homogenates. (J:120737)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Slc16a2 Mutation:
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4 strains or lines available |
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| References |
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Original: |
J:120737
Trajkovic M et al.,
"Abnormal thyroid hormone metabolism in mice lacking the monocarboxylate transporter 8."
J Clin Invest 2007 Mar;117(3):627-35
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All: |
4 reference(s)
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