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| Nomenclature |
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Symbol:
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Tg(Camk2a-Bdnf)A9Stl
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Name:
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transgene insertion A9, Susumu Tonegawa
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MGI ID: |
MGI:3709467 |
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Transgene:
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Tg(Camk2a-Bdnf)A9Stl
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(C57BL/6 x DBA/2)F2
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The transgene construct has the rat Bdnf cDNA sequence, with a Kozak sequence inserted in front of the translation initiation site, controlled by the mouse Camk2a promoter. The SV40 intron/polyA sequence was inserted the 3' to the Bdnf cDNA. ISH demonstrated that Bdnf overexpression is mainly restricted to the forebrain regions, including all of the neocortex, parts of the hippocampus, amygdala and striatum. (J:57645)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:57645
Huang ZJ et al.,
"BDNF regulates the maturation of inhibition and the critical period of plasticity in mouse visual cortex."
Cell 1999 Sep 17;98(6):739-55
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All: |
5 reference(s)
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Analysis Tools
