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| Nomenclature |
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Symbol:
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Drd1atm2Jcd
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Name:
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dopamine receptor D1A;
targeted mutation 2, John Drago
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MGI ID: |
MGI:3707260 |
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Synonyms: |
HZnon-ac |
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Gene:
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Drd1a
Location:
Chr13:54051186-54055658 bp, - strand
Genetic Position: Chr13,
28.4 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:120582
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Parent Cell Line:
| J1 (ES Cell) |
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Strain of Origin:
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129S4/SvJae
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Mutation description |
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Allele
Type: | |
Targeted (knock-in) |
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Mutation: | |
Insertion |
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Mutation details: A targeting vector was designed to insert a transcriptionally silenced attenuated diphtheria toxin (tox-176) gene into the locus. The tox-176 gene was preceeded by a floxed neo-stop cassette. (J:120582)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Drd1a Mutation:
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23 strains or lines available |
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| References |
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Original: |
J:120582
Drago J et al.,
"Targeted expression of a toxin gene to D1 dopamine receptor neurons by cre-mediated site-specific recombination."
J Neurosci 1998 Dec 1;18(23):9845-57
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All: |
4 reference(s)
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