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| Nomenclature |
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Symbol:
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Tg(Ins2-Nos2)31Okam
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Name:
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transgene insertion 31, Hiroshi Okamoto
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MGI ID: |
MGI:3706438 |
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Synonyms: |
line 31 |
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Transgene:
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Tg(Ins2-Nos2)31Okam
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(C57BL/6 x DBA/2)F1
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The transgenic construct was composed of the rat insulin II promoter and the 3.5 kb cDNA fragment containing the entire mouse Nos2 gene coding region with the SV40 intron/polyadenylation signal ligated to it. Line 31 was subsequently established. Western blot analysis shows expression of Nos2 in pancreatic islets, but nowhere else. (J:45520)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:45520
Takamura T et al.,
"Transgenic mice overexpressing type 2 nitric-oxide synthase in pancreatic beta cells develop insulin-dependent diabetes without insulitis."
J Biol Chem 1998 Jan 30;273(5):2493-6
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All: |
1 reference(s)
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Analysis Tools
