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| Nomenclature |
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Symbol:
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Tg(APOC3)3707Bres
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Name:
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transgene insertion 3707, Jan L Breslow
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MGI ID: |
MGI:3703618 |
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Synonyms: |
HuCIII Tg |
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Transgene:
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Tg(APOC3)3707Bres
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(C57BL/6J x CBA/J)F1
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: Male pronuclei of fertilized oocytes were microinjected with a transgenic construct comprising the human apolipoprotein C-III gene, including 2.5 kb of 5' and 1.1 kb of 3' flanking sequence. Mice of this line express the transgene at high levels in the liver and secondarily in the intestine. (J:81184)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:81184
Ito Y et al.,
"Hypertriglyceridemia as a result of human apo CIII gene expression in transgenic mice."
Science 1990 Aug 17;249(4970):790-3
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All: |
7 reference(s)
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Analysis Tools
