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| Nomenclature |
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Symbol:
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Hoxb1tm8(Hoxa1)Mrc
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Name:
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homeobox B1;
targeted mutation 8, Mario R Capecchi
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MGI ID: |
MGI:3702595 |
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Synonyms: |
Hoxb1A1(g) |
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Gene:
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Hoxb1
Location:
Chr11:96365752-96368256 bp, + strand
Genetic Position: Chr11,
59.86 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:119279
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-in) |
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Mutation: | |
Insertion |
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Mutation details: The endogenous coding region was replaced by the homeo box A1 coding region. An IREStauGFP cassette was also inserted into the locus, as well as floxed neo cassette. The neo was subsequently removed by crossing with cre deleter mice. (J:119279)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Hoxb1 Mutation:
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6 strains or lines available |
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| References |
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Original: |
J:119279
Tvrdik P et al.,
"Reversal of Hox1 gene subfunctionalization in the mouse."
Dev Cell 2006 Aug;11(2):239-50
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All: |
1 reference(s)
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Analysis Tools
