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| Nomenclature |
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Symbol:
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Igltm2.1Bgmn
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Name:
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immunoglobulin lambda chain complex;
targeted mutation 2.1, Marianne Bruggemann
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MGI ID: |
MGI:3701069 |
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Synonyms: |
1.3-2.4delta, C1-C2-C3-C4-, L- |
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Gene:
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Igl
Location:
unknown
Genetic Position: Chr16,
Syntenic
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:118712
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Parent Cell Line:
| HM-1 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd-Hprtb-m3
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Deletion |
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Mutation details: LoxP insertions and cre-mediated recombination resulted in a 120Kb deletion spanning C1 through C2, and including C2 and C3. (J:118712)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Igl Mutation:
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0 strains or lines available |
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| References |
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Original: |
J:118712
Zou X et al.,
"Block in development at the pre-B-II to immature B cell stage in mice without Ig kappa and Ig lambda light chain."
J Immunol 2003 Feb 1;170(3):1354-61
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All: |
4 reference(s)
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Analysis Tools
