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| Nomenclature |
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Symbol:
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Spry4tm1Ayos
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Name:
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sprouty homolog 4 (Drosophila);
targeted mutation 1, Akihiko Yoshimura
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MGI ID: |
MGI:3699499 |
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Gene:
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Spry4
Location:
Chr18:38586268-38601268 bp, - strand
Genetic Position: Chr18,
20.5 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:116506
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exon 2 was replaced by a neomycin resistance cassette. Western blot confirmed absence of protein in mutants. (J:116506)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Spry4 Mutation:
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28 strains or lines available |
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| References |
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Original: |
J:116506
Taniguchi K et al.,
"Sprouty2 and Sprouty4 are essential for embryonic morphogenesis and regulation of FGF signaling."
Biochem Biophys Res Commun 2007 Jan 26;352(4):896-902
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All: |
3 reference(s)
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Analysis Tools
