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| Nomenclature |
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Symbol:
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Alms1L2131X
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Name:
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Alstrom syndrome 1;
L2131
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MGI ID: |
MGI:3699224 |
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Gene:
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Alms1
Location:
Chr6:85587531-85702753 bp, + strand
Genetic Position: Chr6,
37.48 cM
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Kidney abnormalities of Alms1L2131X/Alms1L2131X mice at 6 months of age
Show the 3 image(s) involving this allele.
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Mutation
origin |
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Strain of Origin:
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C57BL/6
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Mutation
description |
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Allele
Type: | |
Chemically induced (ENU) |
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Mutation: | |
Nucleotide substitutions |
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Mutation details: This mutation causes premature truncation in exon 10, resulting in the coding of the N-terminal 2131 amino acids of the protein. (J:118221)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Alms1 Mutation:
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9 strains or lines available |
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| References |
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Original: |
J:118221
Li G et al.,
"A Role for Alstrom Syndrome Protein, Alms1, in Kidney Ciliogenesis and Cellular Quiescence."
PLoS Genet 2007 Jan 5;3(1):e8
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All: |
1 reference(s)
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Analysis Tools
