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| Nomenclature |
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Symbol:
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Foxo1tm1Rdp
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Name:
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forkhead box O1;
targeted mutation 1, Ronald DePinho
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MGI ID: |
MGI:3698867 |
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Synonyms: |
Fox1loxP, Foxo1F, Foxo1fl, FoxO1flox, FoxO1L |
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Gene:
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Foxo1
Location:
Chr3:52268337-52350109 bp, + strand
Genetic Position: Chr3,
23.19 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:118179
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Parent Cell Line:
| CJ7 (ES Cell) |
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Strain of Origin:
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129S1/Sv-Oca2+ Tyr+ Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: Exon 2 was flanked with loxP sites. This exon is the first coding exon and contains the N-terminal half of the full-length protein. (J:118179)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Foxo1 Mutation:
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4 strains or lines available |
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| References |
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Original: |
J:118179
Paik JH et al.,
"FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis."
Cell 2007 Jan 26;128(2):309-23
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All: |
47 reference(s)
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Analysis Tools
