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| Nomenclature |
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Symbol:
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Zic3tm1Jwb
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Name:
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zinc finger protein of the cerebellum 3;
targeted mutation 1, John W Belmont
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MGI ID: |
MGI:3698161 |
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Synonyms: |
Zic3neo, Zic3null |
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Gene:
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Zic3
Location:
ChrX:58022700-58041736 bp, + strand
Genetic Position: ChrX,
32.56 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:117748
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Parent Cell Line:
| AB2.2 (ES Cell) |
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Strain of Origin:
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129S7/SvEvBrd-Hprtb-m2
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Mutation description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Insertion |
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Mutation details: An frt-flanked neomycin resistance cassette was inserted in antisense orientation upstream of the locus. (J:117748)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Zic3 Mutation:
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36 strains or lines available |
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| References |
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Original: |
J:117748
Zhu L et al.,
"Craniofacial, skeletal, and cardiac defects associated with altered embryonic murine Zic3 expression following targeted insertion of a PGK-NEO cassette."
Front Biosci 2007;12():1680-90
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All: |
2 reference(s)
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