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| Nomenclature |
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Symbol:
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Hadhbm1Yuan
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Name:
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hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit;
mutation 1, Yuan-Tsong Chen
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MGI ID: |
MGI:3698125 |
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Gene:
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Hadhb
Location:
Chr5:30155248-30184593 bp, + strand
Genetic Position: Chr5,
16.04 cM
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Mutation
origin |
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Strain of Origin:
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C57BL/6J
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Mutation
description |
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Allele
Type: | |
Chemically induced (ENU) |
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Mutation: | |
Single point mutation |
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Mutation details: This allele contains a missense mutation of methionine to lysine at amino acid 404, resulting from a T-to-A transversion in exon 14. (J:117738)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Hadhb Mutation:
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7 strains or lines available |
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| References |
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Original: |
J:117738
Kao HJ et al.,
"ENU mutagenesis identifies mice with cardiac fibrosis and hepatic steatosis caused by a mutation in the mitochondrial trifunctional protein beta-subunit."
Hum Mol Genet 2006 Dec 15;15(24):3569-77
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All: |
1 reference(s)
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Analysis Tools
